I never do calibration cubes. Once you've got your slicer settings working, pretty much the only thing you need to change are the printing speeds and temps.
The rest generally doesn't need changing.

Different brands of pla will perform differently at different temps and seeds. And to a certain extent so will different colours of the same brand.

Generally pla will print best within the 200-215 temp range. Speed wise I usually go somewhere between 40-70 mm/s.
Remember to up the temp a little if you up the speed.

But no, I don't do complicated calibration prints.