Happened to me quite a lot when I first started. I was trying to print a control panel for a box and my print area was just too small (by about 20mm) to do it in one piece. In the end I made it from 2 separate sections and it actually made more sense for the build as it made it easier to swap out the battery. If you're trying to do really big prints (high Z as well as X/Y) you're also risking a lot more filament with a single failure.

It's nice to have the option of a big area, but most of the time now I design around it.