"Would you be more inclined to buy filament designed and manufactured in the EU vs China, bearing in mind the quality benefits and better regulation?"
Neither. Want it made in the US where I can actually get it shipped to me before I die of old age.

"Would you prefer to buy your filament in bespoke boxes of 8, 16 etc. in order to save money per item and on delivery cost?"
Well, if I knew what a bespoke box was...well maybe.