No Clif, with S3d you slice on the pc and upload to octoprint and print. If you want to try a new slicer try the Prusa slicer which is slic3r under full development by Prusa and is free. I still use S3D but an older version as they really screwed up the software in recently releases. It is also fairly clear after using S3d for several year and then trying Prusa, S3D was just Slic3r to start..