I'm trying to find some good settings (will update later this weekend) but I was wondering if I could calculate 'perfect' settings based on the hardware.
So perhaps Mjolinor knows this one ('cause you seem to know a lot of this technical mumbo-jumbo)
How often per second does the motherboard / controller talk to the stepper motors?
What's the smallest step the steppers can make the extruder move in X Y directions?
What's the smallest length of material that can be extruded in one step?

I'm thinking I could use that to calculate which values allow for no floating point values going to the stepper which perhaps allows some small improvements?