While in Prusa Slicer Click on Plater, on the right hand side of the screen you will see
Printer.jpg

Click on the Gear and Select "Add/Remove Presets:"
Click on Other Venders > Creality FFF

Printer1.jpg
Select the Creality Ender-5 > Follow the steps to transfer the Presets to your PrusaSlicer.

With My Prusa i3 compatible I took the Ender 3 Presets and modified for my Hictop 3DP11/12

https://prusaslicerprofiles.com/