Regarding Creality Slcier vs Cura probably not, cure has good Ender 3 / Pro profiles keep the layer speeds the same to start.

Things to change in cura

Temperature for heated bed 60c is a good starting point

Filament temperature depends on the filament but most of the cheaper filament tends to be around the 205c mark and then print a temperature test Look at thingiverse for those

Flow Rate change this with the new value after calibrating the extruder

Retractions will vary even between same machines sometime, but start at 6mm with a speed of around 60mm if possible if not lower speed.

Hope it all helps.