Just to close the loop on this in case anyone has a similar problem in the future, it turned out not to be a design problem, but an adhesive problem. The hairspray works great for PLA, but didn't work as well for the Nylon. Per a YouTube Video entitled "How to: Getting 3d printed Nylon to Stick to the printer bed" (because I don't have enough posts on this board to post links) I tried Elmer's Craft Bond Extra Strength glue stick and my lifting problem went away.