There are no known perisistent effects
excess acetone inhalation causes anosmia - loss of the sense of smell, which also means you can't taste anything.
Not trivial.
Acetone also causes headaches - so regardless of whether or not it;'s a naturally occuring substance - it's not good stuff to be breathing in constantly.

It's also highly combustible.

Just not good stuff to have in an enclosed office or workshop.