The term ‘try and try again’ certainly comes to mind when it comes to latest development regarding Materialise and their application to the FDA for approval of their latest 3D printed guide design. Meant to assist surgeons in the placement of the components involved during knee replacements, this guide was deemed ‘not substantially equivalent. Materialise has, of course, said that they will keep working on it, refining the design with the subsequent feedback from the FDA. Read more at 3DPrint.com: http://3dprint.com/112474/materialise-fda-rejection/